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Put our experience to work for you. Cell Signaling Technology® (CST®) scientists are biology, application, and therapeutic area domain experts and are here to streamline your discovery. We are passionate about science and keep up with all the latest research and new treatment approaches in oncology therapeutic areas, allowing us to offer a broad antibody portfolio against targets that could lead to new, more efficacious therapies.
RNA depletion broadly describes the removal of unwanted, abundant RNA species from a sample. As rRNAs are the most abundant RNA species in most samples, RNA depletion often refers to rRNA depletion, but other species may also be targeted if they obscure a biologically significant readout, as in the case of the depletion of globin mRNA from blood samples. The NEBNext RNA depletion workflow utilizes targeted DNA probes and RNase H to selectively bind to and degrade abundant RNAs.
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Read more hereDNA methylation is the most studied form of epigenetic modification of the genome. Thought primarily to be related to the regulation of gene expression via the inhibition of transcription factor binding, analysis of methylated cytosines within a genome, and across a species’ genomes, can shed light on which genes and regulatory elements are required, or not, at a given point in time. Therefore, the methylome – a genome’s collection of methyl marks – is a changeable snapshot of an organism’s (or a population’s) genomic response to its environment.
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Loop-mediated Isothermal Amplification (LAMP) is a commonly used technique for rapid nucleic acid detection. NEB’s WarmStart LAMP products provide a simple, one-step solution for DNA (LAMP) or RNA (RT-LAMP) targets. Each mix features Bst 2.0 WarmStart DNA Polymerase and WarmStart RTx Reverse Transcriptase, both in silicodesigned enzymes for improved performance in LAMP reactions.
Looking for best-in-class visual detection?
Try our WarmStart Colorimetric LAMP 2X Master Mix with UDG